Počet záznamů: 1

A metal-free DNA nuclease based on a cyclic peptide scaffold

  1. 1.
    0347181 - BFU-R 2011 RIV US eng J - Článek v odborném periodiku
    Alkhader, S. - Ezra, A. - Kašpárková, Jana - Brabec, Viktor - Yavin, E.
    A metal-free DNA nuclease based on a cyclic peptide scaffold.
    Bioconjugate Chemistry. Roč. 21, č. 8 (2010), s. 1425-1431 ISSN 1043-1802
    Grant CEP: GA AV ČR(CZ) IAA400040803; GA MŠk(CZ) LC06030; GA MŠk(CZ) ME08017; GA MŠk(CZ) OC08003; GA AV ČR(CZ) KAN200200651
    Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Klíčová slova: DNA * cleavage * chemical nuclease
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 5.002, rok: 2010

    This work describes DNA nuclease activity of conjugates composed of the cyclic peptide cyc-D-Lys-Gly-Arg-Ser-Arg conjugated to anthraquinone highlighting the various chemical features that are required for efficient DNA degradation by such metal-free DNA cutters.
    Trvalý link: http://hdl.handle.net/11104/0188014