Počet záznamů: 1

Noise exposure during early development impairs the processing of sound intensity in adult rats

  1. 1.
    0345712 - UEM-P 2011 RIV GB eng J - Článek v odborném periodiku
    Bureš, Zbyněk - Grécová, Jolana - Popelář, Jiří - Syka, Josef
    Noise exposure during early development impairs the processing of sound intensity in adult rats.
    European Journal of Neuroscience. Roč. 32, č. 1 (2010), s. 155-164 ISSN 0953-816X
    Grant CEP: GA ČR GA309/07/1336; GA MŠk(CZ) LC554
    Grant ostatní:GA ČR(CZ) GD309/08/H079
    Výzkumný záměr: CEZ:AV0Z50390512
    Klíčová slova: auditory system * critical period * inferior colliculus
    Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
    Impakt faktor: 3.658, rok: 2010

    The study demonstrates that exposure to intense noise at postnatal day 14 produced not only poorer frequency selectivity of neurons in the inferior colliculus (as reported previously by Grecova et al. (2009) Eur. J. Neurosci. 29, 1921–1930), but affected significantly the neuronal representation of sound intensity. Although the response thresholds were similar in the exposed and control rats, the neurons in the exposed animals had a longer first-spike latency, a narrower dynamic range, lower maximum response magnitudes and a steeper slope of the rate–intensity functions. The observed anomalies were confined to the mid- and high-frequency regions, whereas no significant changes were found in the low-frequency neurons.
    Trvalý link: http://hdl.handle.net/11104/0186917