Počet záznamů: 1
Collagen Bioinks for Bioprinting: A Systematic Review of Hydrogel Properties, Bioprinting Parameters, Protocols, and Bioprinted Structure Characteristics
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SYSNO ASEP 0546365 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Collagen Bioinks for Bioprinting: A Systematic Review of Hydrogel Properties, Bioprinting Parameters, Protocols, and Bioprinted Structure Characteristics Tvůrce(i) Štěpanovská, J. (CZ)
Šupová, Monika (USMH-B) RID, ORCID, SAI
Hanzálek, K. (CZ)
Brož, Antonín (FGU-C) RID, ORCID, SAI
Matějka, R. (CZ)Celkový počet autorů 5 Číslo článku 1137 Zdroj.dok. Biomedicines. - : MDPI
Roč. 9, č. 9 (2021)Poč.str. 30 s. Forma vydání Online - E Jazyk dok. eng - angličtina Země vyd. CH - Švýcarsko Klíč. slova bioink ; bioprinting ; collagen ; hydrogel ; hydrogel properties ; bioprinting parameters Vědní obor RIV EI - Biotechnologie a bionika Obor OECD Polymer science CEP NV19-02-00068 GA MZd - Ministerstvo zdravotnictví Způsob publikování Open access Institucionální podpora USMH-B - RVO:67985891 ; FGU-C - RVO:67985823 UT WOS 000699268300001 EID SCOPUS 85114222519 DOI 10.3390/biomedicines9091137 Anotace Bioprinting is a modern tool suitable for creating cell scaffolds and tissue or organ carriers from polymers that mimic tissue properties and create a natural environment for cell development. A wide range of polymers, both natural and synthetic, are used, including extracellular matrix and collagen-based polymers. Bioprinting technologies, based on syringe deposition or laser technologies, are optimal tools for creating precise constructs precisely from the combination of collagen hydrogel and cells. This review describes the different stages of bioprinting, from the extraction of collagen hydrogels and bioink preparation, over the parameters of the printing itself, to the final testing of the constructs. This study mainly focuses on the use of physically crosslinked high-concentrated collagen hydrogels, which represents the optimal way to create a biocompatible 3D construct with sufficient stiffness. The cell viability in these gels is mainly influenced by the composition of the bioink and the parameters of the bioprinting process itself (temperature, pressure, cell density, etc.). In addition, a detailed table is included that lists the bioprinting parameters and composition of custom bioinks from current studies focusing on printing collagen gels without the addition of other polymers. Last but not least, our work also tries to refute the often-mentioned fact that highly concentrated collagen hydrogel is not suitable for 3D bioprinting and cell growth and development. Pracoviště Ústav struktury a mechaniky hornin Kontakt Iva Švihálková, svihalkova@irsm.cas.cz, Tel.: 266 009 216 Rok sběru 2022 Elektronická adresa https://www.mdpi.com/2227-9059/9/9/1137
Počet záznamů: 1