Počet záznamů: 1
Sugared biomaterial binding lectins: achievements and perspectives
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SYSNO ASEP 0462996 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Sugared biomaterial binding lectins: achievements and perspectives Tvůrce(i) Bojarová, Pavla (MBU-M) ORCID
Křen, Vladimír (MBU-M) RID, ORCIDZdroj.dok. Biomaterials Science . - : Royal Society of Chemistry - ISSN 2047-4830
Roč. 4, č. 8 (2016), s. 1142-1160Poč.str. 19 s. Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova C-TYPE LECTINS ; AMPHIPHILIC JANUS GLYCODENDRIMERS ; BIOMEDICALLY RELEVANT LECTINS Vědní obor RIV CE - Biochemie CEP GC15-02578J GA ČR - Grantová agentura ČR Institucionální podpora MBU-M - RVO:61388971 UT WOS 000380895500001 EID SCOPUS 84979265950 DOI 10.1039/c6bm00088f Anotace Lectins, a distinct group of glycan-binding proteins, play a prominent role in the immune system ranging from pathogen recognition and tuning of inflammation to cell adhesion or cellular signalling. The possibilities of their detailed study expanded along with the rapid development of biomaterials in the last decade. The immense knowledge of all aspects of glycan-lectin interactions both in vitro and in vivo may be efficiently used in bioimaging, targeted drug delivery, diagnostic and analytic biological methods. Practically applicable examples comprise photoluminescence and optical biosensors, ingenious three-dimensional carbohydrate microarrays for high-throughput screening, matrices for magnetic resonance imaging, targeted hyperthermal treatment of cancer tissues, selective inhibitors of bacterial toxins and pathogen-recognising lectin receptors, and many others. Pracoviště Mikrobiologický ústav Kontakt Eliška Spurná, eliska.spurna@biomed.cas.cz, Tel.: 241 062 231 Rok sběru 2017
Počet záznamů: 1