Počet záznamů: 1
Impact of air pollution on oxidative DNA damage and lipid peroxidation in mothers and their newborns.
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SYSNO ASEP 0461601 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Impact of air pollution on oxidative DNA damage and lipid peroxidation in mothers and their newborns. Tvůrce(i) Ambrož, Antonín (UEM-P)
Vlková, Veronika (UEM-P)
Rössner ml., Pavel (UEM-P) RID, ORCID
Rössnerová, Andrea (UEM-P) RID
Švecová, Vlasta (UEM-P) RID
Milcová, Alena (UEM-P)
Pulkrabová, J. (CZ)
Hajslová, J. (CZ)
Velemínský Jr., M. (CZ)
Solanský, Ivo (UEM-P)
Šrám, Radim (UEM-P) RIDZdroj.dok. International Journal of Hygiene and Environmental Health. - : Elsevier - ISSN 1438-4639
Roč. 219, č. 6 (2016), s. 545-556Poč.str. 12 s. Jazyk dok. eng - angličtina Země vyd. DE - Německo Klíč. slova air pollution ; benzo[a]pyrene ; lipid peroxidation Vědní obor RIV DN - Vliv životního prostředí na zdraví CEP GA13-13458S GA ČR - Grantová agentura ČR Institucionální podpora UEM-P - RVO:68378041 UT WOS 000381590400008 EID SCOPUS 84994275091 DOI 10.1016/j.ijheh.2016.05.010 Anotace Higher PM2.5 concentrations were found in Karvina than in CB in the summer 2013 (mean +/- SD: 20.41 +/- 6.28 vs. 9.45 +/- 3.62 mu g/m(3), P < 0.001), and in the winter 2014 (mean +/- SD: 53.67 +/- 19.76 vs. 27.96 +/- 12.34 mu g/m(3), P < 0.001). We observed significant differences in 15-F2t-IsoP levels between the summer and winter seasons in Karvina for newborns (mean +/- SD: 64.24 +/- 6.75 vs. 104.26 +/- 38.18 pg/ml plasma, respectively) (P < 0.001). Levels of 8-oxodG differed only in the winter season between localities, they were significantly higher (P <0.001) in newborns from Karvina in comparison with CB (mean SD: 5.70 +/- 2.94 vs. 4.23 +/- 1.51 nmol/mmol creatinine, respectively). The results of multivariate regression analysis in newborns from Karvina showed PM2.5 concentrations to be a significant predictor for 8-oxodG excretion, PM2.5 and B[a]P (benzo[a]pyrene) concentrations to be a significant predictor for 15-F2t-IsoP levels. The results of multivariate regression analysis in mothers showed PM2.5 concentrations to be a significant predictor of 8-oxodG levels. (C) 2016 The Authors. Published by Elsevier GmbH. This is an open access article under the CC BY-NC-ND license. Pracoviště Ústav experimentální medicíny Kontakt Lenka Koželská, lenka.kozelska@iem.cas.cz, Tel.: 241 062 218, 296 442 218 Rok sběru 2017
Počet záznamů: 1