Počet záznamů: 1
Developmental silencing of the AtTERT gene is associated with increased H3K27me3 loading and maintenance of its euchromatic environment
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SYSNO ASEP 0389865 Druh ASEP J - Článek v odborném periodiku Zařazení RIV J - Článek v odborném periodiku Poddruh J Článek ve WOS Název Developmental silencing of the AtTERT gene is associated with increased H3K27me3 loading and maintenance of its euchromatic environment Tvůrce(i) Ogrocká, A. (CZ)
Sýkorová, Eva (BFU-R) RID, ORCID
Fajkus, Jiří (BFU-R) RID, ORCID
Fojtová, M. (CZ)Celkový počet autorů 4 Zdroj.dok. Journal of Experimental Botany. - : Oxford University Press - ISSN 0022-0957
Roč. 63, č. 11 (2012), s. 4233-4241Poč.str. 9 s. Forma vydání Tištěná - P Jazyk dok. eng - angličtina Země vyd. GB - Velká Británie Klíč. slova TELOMERASE REVERSE-TRANSCRIPTASE ; ARABIDOPSIS-THALIANA ; DNA METHYLATION Vědní obor RIV BO - Biofyzika Institucionální podpora BFU-R - RVO:68081707 UT WOS 000306686900021 DOI https://doi.org/10.1093/jxb/ers107 Anotace Telomerase, an enzyme responsible for the maintenance of linear chromosome ends, is precisely regulated during plant development. In animals, involvement of the epigenetic state of the telomerase reverse transcriptase (TERT) gene in the complex regulation of telomerase activity has been reported. To reveal whether epigenetic mechanisms participate in the regulation of plant telomerase, the relationship between telomerase activity in tissues of Arabidopsis thaliana and DNA methylation and histone modifications in the A. thaliana TERT (AtTERT) upstream region was studied. As expected, a gradual decrease of telomerase activity during leaf maturation was observed. A different pattern with a more progressive loss of telomerase activity and AtTERT transcription during leaf development was revealed in MET1 gene-knockout mutants. Analysis of DNA methylation in the AtTERT upstream region showed low levels of methylated cytosines without notable differences between telomerase-positive and telomerase-negative wild-type tissues. Pracoviště Biofyzikální ústav Kontakt Jana Poláková, polakova@ibp.cz, Tel.: 541 517 244 Rok sběru 2013
Počet záznamů: 1