Y chromosome and vimentin used to trace the fate of allogeneic keratinocytes delivered to the wound by the recombined human/pig skin
1.
SYSNO ASEP
0191224
Druh ASEP
J - Článek v odborném periodiku
Zařazení RIV
J - Článek v odborném periodiku
Poddruh J
Ostatní články
Název
Y chromosome and vimentin used to trace the fate of allogeneic keratinocytes delivered to the wound by the recombined human/pig skin
Tvůrce(i)
Pokorná, Eva (UMG-J) Brož, L. (CZ) Veselý, Pavel (UMG-J) Matoušková, Eva (UMG-J)
Zdroj.dok.
Folia Biologica. - : Univerzita Karlova v Praze
- ISSN 0015-5500
Roč. 47, č. 4 (2001), s. 128-134
Poč.str.
7 s.
Jazyk dok.
eng - angličtina
Země vyd.
CZ - Česká republika
Klíč. slova
allogeneic keratinocytes ; xenodermis ; Y-chromosome FISH
Vědní obor RIV
EB - Genetika a molekulární biologie
CEP
IZ4368 GA MZd - Ministerstvo zdravotnictví
NK6126 GA MZd - Ministerstvo zdravotnictví
Anotace
Allogeneic keratinocytes cultured on cell-free pig dermisstimulate wound healing when applied with the epidermal layerfacing the wound. Male keratinocytes were grafted into donorsites of three female patients. Biopsies were taken on days 4, 6 and 9. The Y-chromosome was found (using the fluorescence .I.in situ ./I.hybridization) in donor sites on day 4 and 6, but not on day 9. Conclusion: Allongeneic keratinocytes temporarily "take" to the wound and are replaced by the patient`s cells after about one week.
