Počet záznamů: 1
Age and activation determines the anticonvulsant effect of ifenprodil in rats
- 1.0434262 - FGÚ 2015 RIV DE eng J - Článek v odborném periodiku
Mareš, Pavel
Age and activation determines the anticonvulsant effect of ifenprodil in rats.
Naunyn-Schmiedeberg's Archives of Pharmacology. Roč. 387, č. 8 (2014), s. 753-761. ISSN 0028-1298. E-ISSN 1432-1912
Grant CEP: GA ČR(CZ) GBP304/12/G069
Institucionální podpora: RVO:67985823
Klíčová slova: NMDA receptors * NR2B subunit * anticonvulsant action * ontogeny * rat
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 2.471, rok: 2014
Ifenprodil is an antagonist of MDA receptors containing NR2B subunit. This subunit is dominant at early stages of brain development and therefore the anticonvulsant effect of this drug is marked in very young rats
Trvalý link: http://hdl.handle.net/11104/0238354
Počet záznamů: 1