Počet záznamů: 1
Efficient synthesis of N-alkyl-2,7-dihalocarbazoles by simultaneous carbazole ring closure and N-alkylation
- 1.0377087 - ÚMCH 2013 RIV GB eng J - Článek v odborném periodiku
Výprachtický, Drahomír - Kmínek, Ivan - Pokorná, Veronika - Cimrová, Věra
Efficient synthesis of N-alkyl-2,7-dihalocarbazoles by simultaneous carbazole ring closure and N-alkylation.
Tetrahedron. Roč. 68, č. 25 (2012), s. 5075-5080. ISSN 0040-4020. E-ISSN 1464-5416
Grant CEP: GA MŠMT(CZ) 1M06031; GA ČR GAP106/12/0827
Výzkumný záměr: CEZ:AV0Z40500505
Institucionální podpora: RVO:61389013
Klíčová slova: carbazole ring closure * carbazole alkylation * heterocycles
Kód oboru RIV: JA - Elektronika a optoelektronika, elektrotechnika
Impakt faktor: 2.803, rok: 2012
The N-alkyl-2,7-dihalocarbazole as the main product was formed by the reaction of 4,4′-dihalo-2-nitrobiphenyl with aromatic nitro compound and trialkyl phosphite. The presence and crucial role of aromatic nitro compound causes simultaneous carbazole ring closure and N-alkylation unlike the Cadogan ring closure where non-alkylated carbazole is formed as a main product. In addition, the mixture of aromatic nitro compound and trialkyl phosphite was found to be a possible N-alkylating agent for heterocycles, such as carbazole or indole.
Trvalý link: http://hdl.handle.net/11104/0209341
Počet záznamů: 1