Počet záznamů: 1  

Efficient synthesis of N-alkyl-2,7-dihalocarbazoles by simultaneous carbazole ring closure and N-alkylation

  1. 1.
    0377087 - UMCH-V 2013 RIV GB eng J - Článek v odborném periodiku
    Výprachtický, Drahomír - Kmínek, Ivan - Pokorná, Veronika - Cimrová, Věra
    Efficient synthesis of N-alkyl-2,7-dihalocarbazoles by simultaneous carbazole ring closure and N-alkylation.
    Tetrahedron. Roč. 68, č. 25 (2012), s. 5075-5080. ISSN 0040-4020
    Grant CEP: GA MŠk(CZ) 1M06031; GA ČR GAP106/12/0827
    Výzkumný záměr: CEZ:AV0Z40500505
    Institucionální podpora: RVO:61389013
    Klíčová slova: carbazole ring closure * carbazole alkylation * heterocycles
    Kód oboru RIV: JA - Elektronika a optoelektronika, elektrotechnika
    Impakt faktor: 2.803, rok: 2012

    The N-alkyl-2,7-dihalocarbazole as the main product was formed by the reaction of 4,4′-dihalo-2-nitrobiphenyl with aromatic nitro compound and trialkyl phosphite. The presence and crucial role of aromatic nitro compound causes simultaneous carbazole ring closure and N-alkylation unlike the Cadogan ring closure where non-alkylated carbazole is formed as a main product. In addition, the mixture of aromatic nitro compound and trialkyl phosphite was found to be a possible N-alkylating agent for heterocycles, such as carbazole or indole.
    Trvalý link: http://hdl.handle.net/11104/0209341