Počet záznamů: 1  

Voltammetric Determination of Tumor Biomarkers for Neuroblastoma (Homovanillic Acid, Vanillylmandelic Acid, and 5-Hydroxyindole-3-acetic Acid) at Screen-printed Carbon Electrodes

  1. 1. 0466719 - UFCH-W 2018 RIV DE eng J - Článek v odborném periodiku
    Makrlíková, Anna - Ktena, E. - Economou, A. - Fischer, J. - Navrátil, Tomáš - Barek, J. - Vyskočil, V.
    Voltammetric Determination of Tumor Biomarkers for Neuroblastoma (Homovanillic Acid, Vanillylmandelic Acid, and 5-Hydroxyindole-3-acetic Acid) at Screen-printed Carbon Electrodes.
    Electroanalysis. Roč. 29, č. 1 (2017), s. 146-153 ISSN 1040-0397
    Institucionální podpora: RVO:61388955
    Klíčová slova: Homovanillic acid * Vanillylmandelic acid * 5-Hydroxyindole-3-acetic acid
    Kód oboru RIV: CG - Elektrochemie
    Obor OECD: Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)
    Impakt faktor: 2.851, rok: 2017

    Three tumor biomarkers (homovanillic acid
    (HVA), vanillylmandelic acid (VMA), and 5-hydroxyindole-
    3-acetic acid (5-HIAA)) have been determined by
    differential pulse voltammetry (DPV) at screen-printed
    carbon electrodes (SPCEs). As an optimum medium for
    all three analytes, Britton-Robinson buffer (0.04 mol·L 1,
    pH 3.0) was used. Dependencies of the peak current on
    the concentration of a biomarker were linear in the concentration
    range from 0.2 to 100 mmol·L 1 for all the
    tested compounds, with the limits of quantification
    0.8 mmol·L 1 for homovanillic acid, 0.2 mmol·L 1 for vanillylmandelic
    acid, and 0.4 mmol·L 1 for 5-hydroxyindole-
    3-acetic acid. Moreover, it was verified that the
    newly developed methods can be used for simultaneous
    determination of HVA and VMA in mixture.
    Trvalý link: http://hdl.handle.net/11104/0264962
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