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Carbohydrate-modified magnetic nanoparticles for radical scavenging

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    0463728 - ÚMCH 2017 RIV CZ eng J - Článek v odborném periodiku
    Moskvin, Maksym - Horák, Daniel
    Carbohydrate-modified magnetic nanoparticles for radical scavenging.
    Physiological Research. Roč. 65, Suppl. 2 (2016), S243-S251. ISSN 0862-8408. E-ISSN 1802-9973
    Grant CEP: GA MŠk(CZ) LQ1604
    Institucionální podpora: RVO:61389013
    Klíčová slova: magnetic nanoparticles * silica * glucose
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 1.461, rok: 2016
    http://www.biomed.cas.cz/physiolres/pdf/65%20Suppl%202/65_S243.pdf

    Maghemite (gamma-Fe2O3) nanoparticles, 12 nm in size, were prepared by co-precipitation of Fe(II) and Fe(III) chlorides with ammonium hydroxide and oxidation with hydrogen peroxide. To achieve stability and biocompatibility, obtained particles were coated with silica, to which glucose and ascorbic acid were bound by different mechanisms. The composite particles were thoroughly characterized by transmission electron microscopy, dynamic light scattering, elemental analysis, and FT-Raman and fluorescence spectroscopy to determine composition, morphology, size and its distribution, zeta-potential, and scavenging of peroxyl and hydroxyl radicals. As the particles showed promising antioxidative properties, they may have a possible application as a stable magnetically controlled scavenger of reactive oxygen species.
    Trvalý link: http://hdl.handle.net/11104/0264464

     
     
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