Počet záznamů: 1  

New species of Torque Teno miniviruses infecting gorillas and chimpanzees

  1. 1.
    0461949 - BC-A 2017 RIV US eng J - Článek v odborném periodiku
    Hrazdilová, K. - Slaninková, E. - Brožová, K. - Modrý, David - Vodička, R. - Celer, V.
    New species of Torque Teno miniviruses infecting gorillas and chimpanzees.
    Virology. Roč. 487, JAN (2016), s. 207-214. ISSN 0042-6822
    Institucionální podpora: RVO:60077344
    Klíčová slova: Anellovirus * Torque Teno mini virus * Great apes * Non-human primates * Genome sequence
    Kód oboru RIV: FN - Epidemiologie, infek. nemoci a klin. imunologie
    Impakt faktor: 3.353, rok: 2016

    Anelloviridae family is comprised of small, non-enveloped viruses of various genome lengths, high sequence diversity, sharing the same genome organization. Infections and co-infections by different genotypes in humans are ubiquitous. Related viruses were described in number of mammalian hosts, but very limited data are available from the closest human relatives - great apes and non-human primates.

    Here we report the 100% prevalence determined by semi-nested PCR from fecal samples of 16 captive primate species. Only the Mandrillus sphinx, showed the prevalence only 8%. We describe three new species of gorillas' and four new species of chimpanzees' Betatorqueviruses and their co-infections in one individual. This study is also first report and analysis of nearly full length TTMV genomes infecting gorillas. Our attempts to sequence the complete genomes of anelloviruses from host feces invariably failed. Broader usage of blood /tissue material is necessary to understand the diversity and interspecies transmission of anelloviruses.
    Trvalý link: http://hdl.handle.net/11104/0261489