Počet záznamů: 1  

A Deep Insight Into the Sialotranscriptome of the Chagas Disease Vector, Panstrongylus megistus (Hemiptera: Heteroptera)

  1. 1.
    0451298 - BC-A 2016 RIV US eng J - Článek v odborném periodiku
    Ribeiro, J.M.C. - Schwarz, Alexandra - Francischetti, I.M.B.
    A Deep Insight Into the Sialotranscriptome of the Chagas Disease Vector, Panstrongylus megistus (Hemiptera: Heteroptera).
    Journal of Medical Entomology. Roč. 52, č. 3 (2015), s. 351-358. ISSN 0022-2585
    Grant CEP: GA MŠk LH12002; GA ČR GPP302/11/P798
    Institucionální podpora: RVO:60077344
    Klíčová slova: Chagas disease * vector biology * salivary gland * transcriptome * medical entomology
    Kód oboru RIV: FN - Epidemiologie, infek. nemoci a klin. imunologie
    Impakt faktor: 1.712, rok: 2015

    Saliva of blood-sucking arthropods contains a complex cocktail of pharmacologically active compounds that assists feeding by counteracting their hosts' hemostatic and inflammatory reactions. Panstrongylus megistus (Burmeister) is an important vector of Chagas disease in South America, but despite its importance there is only one salivary protein sequence publicly deposited in GenBank. In the present work, we used Illumina technology to disclose and publicly deposit 3,703 coding sequences obtained from the assembly of >70 million reads. These sequences should assist proteomic experiments aimed at identifying pharmacologically active proteins and immunological markers of vector exposure.
    Trvalý link: http://hdl.handle.net/11104/0252494