Počet záznamů: 1  

Tetracycline-inducible gene expression system in Leishmania mexicana

  1. 1. 0439435 - BC-A 2015 RIV NL eng J - Článek v odborném periodiku
    Kraeva, N. - Ishemgulova, A. - Lukeš, Julius - Yurchenko, Vyacheslav
    Tetracycline-inducible gene expression system in Leishmania mexicana.
    Molecular and Biochemical Parasitology. Roč. 198, č. 1 (2014), s. 11-13 ISSN 0166-6851
    Grant CEP: GA MŠk(CZ) EE2.3.30.0032
    Institucionální podpora: RVO:60077344
    Klíčová slova: Leishmania mexicana * Gene expression * Tet-inducible system
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 1.787, rok: 2014

    Here we present a T7-driven, tetracycline-inducible system for protein expression in human pathogen Leishmania mexicana. The gene expression in this strain is tightly regulated and dose- and timedependent. This system can be widely used by the parasitology community to analyze effects of genes of interest on biology, physiology and virulence of parasites causing cutaneous leishmaniases.
    Trvalý link: http://hdl.handle.net/11104/0242742