0435329 - FZÚ 2015 RIV US eng J - Článek v odborném periodiku
Ghoran, S.H. - Saeidnia, S. - Babaei, E. - Kiuchi, F. - Dušek, Michal - Eigner, Václav - Khalaji, A.D. - Soltani, A.
Biochemical and biophysical properties of a novel homoisoflavonoid extracted from Scilla persica HAUSSKN.
Bioorganic Chemistry. Roč. 57, DEC (2014), s. 51-56. ISSN 0045-2068. E-ISSN 1090-2120
Grant CEP: GA ČR(CZ) GA14-03276S
Institucionální podpora: RVO:68378271
Klíčová slova: Scillapersicone * Liliaceae * Scilla persica * single-crystal X-ray diffraction * theoretical analysis
Kód oboru RIV: BM - Fyzika pevných látek a magnetismus
Impakt faktor: 2.152, rok: 2014

In this study isolation and structural elucidation of a homoisoflavonoid, 3-(30,40-dihydroxybenzyl)-8-hydroxy-5,7-dimethoxychroman-4-one (Scillapersicone), is reported from Scilla persica HAUSSKN. The structure was solved by a single crystal X-ray analysis. The structure was consistent with the UV, IR, 1D and 2D NMR, HRFAB-MS data. The optimized molecular geometry agrees closely that obtained from the single crystal X-ray crystallography. Furthermore, cytotoxicity of this compound was evaluated by MTT assay on AGS and WEHI-164 cancerous cell lines.
Trvalý link: http://hdl.handle.net/11104/0239187