Počet záznamů: 1  

Time-regulated drug delivery system based on coaxially incorporated platelet alpha-granules for biomedical use

  1. 1. 0397661 - UEM-P 2014 RIV GB eng J - Článek v odborném periodiku
    Buzgo, Matej - Jakubová, Radka - Míčková, Andrea - Rampichová, Michala - Prosecká, Eva - Kochová, P. - Lukáš, D. - Amler, Evžen
    Time-regulated drug delivery system based on coaxially incorporated platelet alpha-granules for biomedical use.
    Nanomedicine. Roč. 8, č. 7 (2013), s. 1137-1154 ISSN 1743-5889
    Grant CEP: GA ČR GAP304/10/1307
    Grant ostatní:GA UK(CZ) 330611; GA UK(CZ) 384311; GA UK(CZ) 626012; GA MŠk(CZ) ME10145; GA MZd(CZ) NT12156
    Výzkumný záměr: CEZ:AV0Z50390703; CEZ:AV0Z50390512
    Klíčová slova: Core-shell nanofibers * alpha granules * cartilage tissue engineering
    Kód oboru RIV: FP - Ostatní lékařské obory
    Impakt faktor: 5.824, rok: 2013

    Alpha granules are novel source of natural growth factors from platelets. In recent work we had sucesfully embedded alpha granules into nanofibers with core/shell structure. The alpha granules survived the electrospinning proces and growth factors retained their bioaktivity as was demonstarted on the model of chondrocytes and mesenchymal stem cells.
    Trvalý link: http://hdl.handle.net/11104/0225293