0383863 - ÚEM 2013 RIV DE eng J - Článek v odborném periodiku
Lemos, J. R. - Ortiz-Miranda, S. I. - Cuadra, A. E. - Velazquez-Marrero, C. - Custer, E. E. - Dad, T. - Dayanithi, Govindan
Modulation/physiology of calcium channel sub-types in neurosecretory terminals.
Cell Calcium. Roč. 51, 3-4 (2012), s. 284-292. ISSN 0143-4160. E-ISSN 1532-1991
Grant CEP: GA ČR(CZ) GAP303/11/0192; GA ČR GAP304/11/2373
Výzkumný záměr: CEZ:AV0Z50390703
Institucionální podpora: RVO:68378041
Klíčová slova: Calcium channels * ATP * Adenosine
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 4.327, rok: 2012 ; AIS: 1.341, rok: 2012
DOI: https://doi.org/10.1016/j.ceca.2012.01.008

The hypothalamic-neurohypophysial system (HNS) controls diuresis and parturition through the release of arginine-vasopressin (AVP) and oxytocin (OT). These HNS neurons develop specific electrical activity (bursts) in response to various physiological stimuli. The release of AVP and OT at the level of neurohypophysis is directly linked not only to their different burst patterns, but is also regulated by the activity of a number of voltage-dependent channels present in the HNS nerve terminals and by feedback modulators. We conclude by proposing a model that can explain how purinergic and/or opioid feedback modulation during bursts can mediate differences in the control of neurohypophysial AVP vs. OT release.
Trvalý link: http://hdl.handle.net/11104/0213673