0379146 - BFÚ 2013 RIV US eng J - Článek v odborném periodiku
Betanzos-Lara, S. - Salassa, L. - Habtemariam, A. - Nováková, Olga - Pizarro, A.M. - Clarkson, G.J. - Lišková, Barbora - Brabec, Viktor - Sadler, P.J.
Photoactivatable organometallic pyridyl ruthenium(II) arene complexes.
Organometallics. Roč. 31, č. 9 (2012), s. 3466-3479. ISSN 0276-7333. E-ISSN 1520-6041
Grant CEP: GA ČR(CZ) GD301/09/H004
Výzkumný záměr: CEZ:AV0Z50040702
Klíčová slova: ruthenium(II) arene complexes * photochemotherapy * DNA binding
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 4.145, rok: 2012

Photoactivatable Organometallic pyridyl ruthenium(II) arene complexes can selectively photodissociate the monodentate ligand when excited with UVA or white light, allowing strict control of the formation of the reactive aqua species. Calf thymus (CT)-DNA binding studies showed that the irradiated complexes bind to CT-DNA, whereas the nonirradiated forms bind negligibly.
Trvalý link: http://hdl.handle.net/11104/0210410