Počet záznamů: 1  

Immunochemical detection of oxidatively damaged DNA

  1. 1. 0377754 - UEM-P 2013 RIV GB eng J - Článek v odborném periodiku
    Rössner ml., Pavel - Šrám, Radim
    Immunochemical detection of oxidatively damaged DNA.
    Free Radical Research. Roč. 46, č. 4 (2012), s. 492-522. ISSN 1071-5762
    Grant CEP: GA MŽP(CZ) SP/1B3/50/07; GA MŠk 2B08005; GA ČR GAP503/11/0084
    Výzkumný záměr: CEZ:AV0Z50390703
    Institucionální podpora: RVO:68378041
    Klíčová slova: oxidative DNA damage * ELISA * immunohistochemistry
    Kód oboru RIV: DN - Vliv životního prostředí na zdraví
    Impakt faktor: 3.279, rok: 2012

    Several methods have been developed to detect oxidatively damaged DNA. This review evaluates the studies dealing with the detection of 8-oxodG in humans, the most abundant oxidized nucleoside. Authors concentrated especially on studies which used enzyme linked immunosorbent assay and immunohistochemistry to detect 8-oxodG in humans, laboratory animals and in cell lines. Oxidative damage observed in these organisms resulted from disease, exposure to environmental pollutants of from in vitro treatment with various chemical and physical factors.
    Trvalý link: http://hdl.handle.net/11104/0209834