Počet záznamů: 1
Differential Modulation of N-Type Calcium Channels by mu-Opioid Receptors in Oxytocinergic Versus Vasopressinergic Neurohypophysial Terminals
- 1.0349372 - ÚEM 2011 RIV US eng J - Článek v odborném periodiku
Ortiz-Miranda, S. I. - Dayanithi, Govindan - Velazquez-Marrero, C. - Custer, E. E. - Treistman, S. N. - Lemos, J. R.
Differential Modulation of N-Type Calcium Channels by mu-Opioid Receptors in Oxytocinergic Versus Vasopressinergic Neurohypophysial Terminals.
Journal of Cellular Physiology. Roč. 225, č. 1 (2010), s. 276-288. ISSN 0021-9541. E-ISSN 1097-4652
Výzkumný záměr: CEZ:AV0Z50390703
Klíčová slova: magnocellular neurons * G-protein modulation * neurohypophysis
Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
Impakt faktor: 3.986, rok: 2010
http://arl-repository.lib.cas.cz/uloziste_av/UEM-P/cav_un_epca-0349372_01.pdf
Opioids modulate the electrical activity of magnocellular neurons (MCN) and inhibit neuropeptide release at their terminals in the neurohypophysis. We show that micro-opioid receptor (MOR) activation induces a stronger inhibition of oxytocin (OT) than vasopressin (AVP) release from isolated MCN terminals and found that N-type calcium channels in AVP terminals are differentially modulated by MOR.
Trvalý link: http://hdl.handle.net/11104/0189629
Počet záznamů: 1