Počet záznamů: 1
Effects of gamma irradiation on the DNA-protein complex between the estrogen response element and the estrogen receptor
- 1.0345749 - ÚJF 2011 RIV GB eng J - Článek v odborném periodiku
Štísová, Viktorie - Goffinont, S. - Maurizot, M. S. - Davídková, Marie
Effects of gamma irradiation on the DNA-protein complex between the estrogen response element and the estrogen receptor.
Radiation Physics and Chemistry. Roč. 79, č. 8 (2010), s. 880-889. ISSN 0969-806X. E-ISSN 1879-0895
Grant CEP: GA MŠMT 1P05OC085; GA MŠMT OC09012
Výzkumný záměr: CEZ:AV0Z10480505
Klíčová slova: DNA-protein complex * estrogen response element * estrogen receptor * ionizing radiation
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 1.132, rok: 2010
The radiosensitivity in vitro of the complex between ER alpha, a subtype of this receptor, and a DNA fragment bearing ERE, as well as the influence of an estrogen (estradiol) or an anti-estrogen (tamoxifen) on this radiosensitivity were studied. We observed that the complex is destabilized upon irradiation with gamma rays in aerated aqueous solution.
Trvalý link: http://hdl.handle.net/11104/0186949
Počet záznamů: 1