Počet záznamů: 1
Increased liver oxidative stress and altered PUFA metabolism precede development of non-alcoholic steatohepatitis in SREBP-1a transgenic spontaneously hypertensive rats with genetic predisposition to hepatic steatosis
- 1.0341813 - FGÚ 2011 RIV US eng J - Článek v odborném periodiku
Malínská, H. - Oliyarnyk, O. - Hubová, M. - Zídek, Václav - Landa, Vladimír - Šimáková, Miroslava - Mlejnek, Petr - Kazdová, L. - Kurtz, T. W. - Pravenec, Michal
Increased liver oxidative stress and altered PUFA metabolism precede development of non-alcoholic steatohepatitis in SREBP-1a transgenic spontaneously hypertensive rats with genetic predisposition to hepatic steatosis.
Molecular and Cellular Biochemistry. Roč. 335, 1-2 (2010), s. 119-125. ISSN 0300-8177. E-ISSN 1573-4919
Grant CEP: GA AV ČR(CZ) IAA500110604; GA MZd(CZ) NR9387; GA MZd(CZ) NR9359
Grant ostatní: EC(XE) LSHG-CT-2005-019015
Výzkumný záměr: CEZ:AV0Z50110509
Klíčová slova: hepatic steatosis * oxidative stress * fatty acid composition
Kód oboru RIV: FB - Endokrinologie, diabetologie, metabolizmus, výživa
Impakt faktor: 2.168, rok: 2010
Increased liver oxidative stress and altered PUFA metabolism precede development of non-alcoholic steatohepatitis in SREBP-1a transgenic spontaneously hypertensive rats with genetic predisposition to hepatic steatosis.These results are consistent with the hypothesis that excess fat accumulation in the liver in association with increased oxidative stress and disturbances in the metabolism of saturated and unsaturated fatty acids may precede and contribute to the primary pathogenesis of NASH
Trvalý link: http://hdl.handle.net/11104/0184686
Počet záznamů: 1