0193792 - UOCHB-X 20000224 RIV CZ eng J - Článek v odborném periodiku
Hlaváček, Jan - Marcová, Renata - Buděšínský, Miloš - Slaninová, Jiřina
1-deamino-1(15)-carba and -dicarba analogues of endothelin-1.
Collection of Czechoslovak Chemical Communications. Roč. 65, č. 3 (2000), s. 407-424. ISSN 0010-0765
Grant CEP: GA ČR GA203/97/0155; GA ČR GA203/98/1330
Výzkumný záměr: CEZ:AV0Z4055905
Kód oboru RIV: CC - Organická chemie
Impakt faktor: 0.960, rok: 2000

The carba and di-carba analogues of endothelin-1 were synthesized either by a fragment condensation of protected cyclic pentadecapeptides with carboxy-terminal hexapeptides or by step-wise coupling on polymer support from carboxy-terminus. Analogues were devoid of uterotonic activity in comparison with the parent endothelin-1.
Trvalý link: http://hdl.handle.net/11104/0089484