0173753 - UEM-P 20033077 RIV GB eng M - Část monografie knihy
Šrám, Radim - Binková, Blanka
Biomonitoring of occupational exposure to chemical carcinogens.
Human Monitoring for Genetic Effects. Amsterdam: IOS Press, 2003 - (Cebulska-Wasilewska, A.; Au, W.; Šrám, R.), s. 44-48. NATO Sci. Series I., 351
Grant ostatní: EC(XE) QLK4-CT-2002-02831
Výzkumný záměr: CEZ:AV0Z5039906
Klíčová slova: polycyclic aromatic hydrocarbons * occupational exposure * biomarkers of exposure
Kód oboru RIV: EB - Genetika a molekulární biologie

The use of different biomarkers for occupational exposure to carcinogenic polycyclic aromatic hydrocarbons (coke-oven workers) was assessed. As sensitive biomarkers of exposure were evaluated metabolite 1-OH-pyrene in urine, DNA adducts by 32P-postlabeling, as biomarkers of effects chromosomal aberrations and SCE, as biomarkers of susceptibility CYP1A1 Ile/Val and MspI polymorphisms.
Trvalý link: http://hdl.handle.net/11104/0070779