0142568 - FGU-C 20030164 RIV NL eng J - Článek v odborném periodiku
Kretschmannová, Karla - Svobodová, Irena - Zemková, Hana
Day-night variations in zinc sensitivity of GABA(A) receptor-channels in rat suprachiasmatic nucleus.
Molecular Brain Research. Roč. 120, č. 1 (2003), s. 46-51. ISSN 0169-328X
Grant CEP: GA ČR GA309/02/1519; GA AV ČR IAA5011103; GA AV ČR IAA5011105
Výzkumný záměr: CEZ:AV0Z5011922
Klíčová slova: GABA * circadian rhythm * suprachiasmatic nuclei
Kód oboru RIV: ED - Fyziologie
Impakt faktor: 2.107, rok: 2003

In SCN neurons maintained in brain slices, but not in other neurons, the zinc sensitivity of GABAA receptor-channels varied with daily time. During the day, the calculated IC50 for zinc was significantly lower than during the night. These results indicate that proportionality of GABAA receptors having and not having ( subunit in SCN neurons changes during the day and night.
Trvalý link: http://hdl.handle.net/11104/0040269