Počet záznamů: 1  

Impedance analysis of DNA and DNA-drug interactions on thin mercury film electrodes

  1. 1.
    0126753 - BFU-R 20023052 RIV US eng J - Článek v odborném periodiku
    Hasoň, Stanislav - Dvořák, Jakub - Jelen, František - Vetterl, Vladimír
    Impedance analysis of DNA and DNA-drug interactions on thin mercury film electrodes.
    Critical Reviews in Analytical Chemistry. Roč. 32, č. 2 (2002), s. 167-179. ISSN 1040-8347
    Grant CEP: GA AV ČR IAA4004901; GA AV ČR IAA4004002; GA AV ČR IBS5004107
    Grant ostatní:GA FRVŠ(XC) G40583; GA FRVŠ(XC) F40564
    Výzkumný záměr: CEZ:AV0Z5004920
    Klíčová slova: electrochemical impedance spectroscopy * intercalators * DNA at electrode surface
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 2.074, rok: 2002

    In this review we briefly summarize the results of impedance measurements (dependence of the differential capacitance C and/or impedance Z of the electrode double layer on potential E, C-E curves) or on frequency (Electrochemical Impedance Spectroscopy-EIS) of nucleic acids at mercury film electrode (MFE). Mercury film was plated either on a glassy carbon electrode (GCE) or pyrolytic graphite electrode (PGE). The dependence of the pseudocapacitance redox peak of echinomycin on concentration and on the ac voltage frequency was measured in bulk solution. Interaction of single- and double-stranded DNA with bis-intercalator echinomycin at nucleic acid-modified surface was studied using EIS with adsorptive transfer method.
    Trvalý link: http://hdl.handle.net/11104/0024981