Adsorptive Transfer Stripping AC Voltammetry of DNA Complexes with Intercalators

0126373 - BFU-R 20000191 RIV US eng J - Článek v odborném periodiku
Fojta, Miroslav - Havran, Luděk - Fulnečková, Jana - Kubičárová, Tatiana
Adsorptive Transfer Stripping AC Voltammetry of DNA Complexes with Intercalators.
Electroanalysis. Roč. 12, č. 12 (2000), s. 926-934. ISSN 1040-0397. E-ISSN 1521-4109
Grant CEP: GA AV ČR IAA4004801; GA ČR GA204/98/P091; GA ČR GV204/97/K084
Výzkumný záměr: CEZ:AV0Z5004920
Kód oboru RIV: BO - Biofyzika
Impakt faktor: 1.972, rok: 2000

Using alternating current adsorptive transfer stripping voltammetry at hanging mercury drop electrode, conformational changes of DNA due to binding of DNA intercalators were studied. After medium exchange and intercalator removal, the surface-confined DNA probably adopted a restrained structure which was resistent to DNA surface denaturation. Upon introduction of DNA single-strand breaks, the specific behavior of DNA-intercalator complexes was eliminated.
Trvalý link: http://hdl.handle.net/11104/0024603