Počet záznamů: 1

Modulation of gap-junctional intercellular communication by a series of cyanobacterial samples from nature and laboratory cultures

  1. 1.
    0369524 - BU-J 2012 RIV GB eng J - Článek v odborném periodiku
    Nováková, K. - Babica, Pavel - Adamovský, O. - Bláha, Luděk
    Modulation of gap-junctional intercellular communication by a series of cyanobacterial samples from nature and laboratory cultures.
    Toxicon. Roč. 58, č. 1 (2011), s. 76-84 ISSN 0041-0101
    Grant CEP: GA ČR GA524/08/0496
    Výzkumný záměr: CEZ:AV0Z60050516
    Klíčová slova: cyanotoxins * gap-junctional intercellular communication * tumor promotion
    Kód oboru RIV: EF - Botanika
    Impakt faktor: 2.508, rok: 2011

    Extracts and exudates of cyanobacteria inhibit gap-junctional intercellular communication in rat liver cells in vitro. Inhibitory effects on GJIC were caused by chemicals different from microcystin and cylindrospermopsin, which indicates an existence of novel tumor promoting cyanotoxins. The effects were induced by common bloom-forming cyanobacteria (Anabaena, Aphanizomenon, Microcystis, Planktothrix), but the inhibitory potencies of extrats and exudates were species- and strain-specific.
    Trvalý link: http://hdl.handle.net/11104/0203567