Počet záznamů: 1

Hydrogel Scaffolds Contribute to the Ostogenesis and Chondrogenesis in the Small Osteochongral Defects

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    0367638 - UFCH-W 2012 RIV HR eng M - Část monografie knihy
    Petrtýl, M. - Lísal, J. - Šenolt, L. - Bastl, Zdeněk - Kruliš, Zdeněk - Polanská, M. - Hulejová, H. - Černý, P. - Danešová, J.
    Hydrogel Scaffolds Contribute to the Ostogenesis and Chondrogenesis in the Small Osteochongral Defects.
    Biomaterials Applications for Nanomedicine. Rijeka: InTech, 2011 - (Pignatello, R.), s. 53-68. ISBN 978-953-307-661-4
    Grant CEP: GA ČR GA106/06/0761
    Výzkumný záměr: CEZ:AV0Z40400503; CEZ:AV0Z40500505
    Klíčová slova: osteogenesis * chondrogenesis * physical chemistry
    Kód oboru RIV: CF - Fyzikální chemie a teoretická chemie

    Hyaline cartilage shows only a limited response to self-repair (Hunter, 1743). Many people are stricken with degenerative osteochondral defects. Modern therapies of osteochondral defects are focused (for example) on the transplantation of osteochondral autografts, rushed spongiosa with collagen, chondrocytes and many others. The insertion of a crushed autologous bone graft has been reported as a possible therapy. However, the regenerative biomechanical (material) quality was less than 70% of healthy cartilage for fragments and controls (Kleemann et al., 2006). The transplantation of autologous osteochondral 3Dcylinders is one of several surgical therapies (Horas, 2003). During operations osteochondral defects are filled with material of a natural histological structure.
    Trvalý link: http://hdl.handle.net/11104/0202235