Počet záznamů: 1

Phylogeny, longevity and evolution of adaptive immunity

  1. 1.
    0367535 - UBO-W 2012 RIV CZ eng J - Článek v odborném periodiku
    Vinkler, Michal - Albrecht, Tomáš
    Phylogeny, longevity and evolution of adaptive immunity.
    Folia zoologica. Roč. 60, č. 3 (2011), s. 277-282 ISSN 0139-7893
    Grant CEP: GA ČR GA206/08/0640; GA ČR GA206/08/1281; GA ČR GAP505/10/1871
    Výzkumný záměr: CEZ:AV0Z60930519
    Klíčová slova: acquired immunity * evolutionary immunology * immunological priming * innate immunity * invertebrates
    Kód oboru RIV: EG - Zoologie
    Impakt faktor: 0.554, rok: 2011

    Adaptive immunity is commonly viewed as a unique vertebrate feature. A misleading view on vertebrate longevity compared to non-vertebrate animals together with oversimplification of 'invertebrate' phylogeny sometimes serves for justifying the limitation of adaptive immunity exclusively to vertebrates. However, here we emphasise that the borderline for differentiation between 'innate' and 'adaptive' immunity may be fuzzy and artificial. In invertebrates with a long lifespan some kind of acquired immunity could exist. We therefore stress that the definition of 'adaptivity' of immune response should reflect the system function instead of a certain molecular mechanism adopted. If these altered criteria are considered then several pieces of recent evidence indicate that the adaptive immunity in animals might have arisen several times independently and in very different forms.
    Trvalý link: http://hdl.handle.net/11104/0202181
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