Počet záznamů: 1

Involvement of the subthalamic nucleus and globus pallidus internus in attention

  1. 1.
    0366075 - UPT-D 2012 RIV AT eng J - Článek v odborném periodiku
    Bocková, M. - Chládek, Jan - Jurák, Pavel - Halámek, Josef - Baláž, M. - Rektor, I.
    Involvement of the subthalamic nucleus and globus pallidus internus in attention.
    Journal of Neural Transmission. Roč. 118, č. 8 (2011), s. 1235-1245 ISSN 0300-9564
    Grant CEP: GA AV ČR IAA200650801; GA MŠk ED0017/01/01
    Výzkumný záměr: CEZ:AV0Z20650511
    Klíčová slova: basal ganglia * ERP * ERD/S * attention * DBS
    Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
    Impakt faktor: 2.730, rok: 2011

    We studied the appearance of cognitive event-related potentials (ERPs) and event-related de/synchronizations (ERD/S) in the subthalamic nucleus (STN) and globus pallidus internus (GPi). We particularly focused on the rare non-target (distractor) stimuli processing. ERPs and ERD/S in the alpha and beta frequency range were analyzed in seven Parkinson's disease patients and one primary dystonia patient with implanted deep brain stimulation (DBS) electrodes. A visual three-stimulus protocol was used (frequent stimulus, target stimulus, and distractor). The non-target and distractor-related waveforms manifested similar shapes. A specific positive ERP peak around 200 ms and a low alpha frequency ERS were detected from the STN as a response to the distractor stimuli in six of the patients with Parkinson's disease and also in the primary dystonia patient's GPi. This positivity probably reflects an attentional orienting response to the distractor stimuli.
    Trvalý link: http://hdl.handle.net/11104/0201166