Počet záznamů: 1

Crystallization and diffraction analysis of thioredoxin reductase from Streptomyces coelicolor

  1. 1.
    0366023 - UOCHB-X 2012 RIV GB eng J - Článek v odborném periodiku
    Koháryová, M. - Brynda, Jiří - Řezáčová, Pavlína - Kollárová, M.
    Crystallization and diffraction analysis of thioredoxin reductase from Streptomyces coelicolor.
    Acta Crystallographica Section F. F67, č. 8 (2011), s. 917-921 ISSN 1744-3091
    Výzkumný záměr: CEZ:AV0Z40550506; CEZ:AV0Z50520514
    Klíčová slova: flavoenzymes * potential antibiotic target * crystallization
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 0.506, rok: 2011

    Thioredoxin reductases are homodimeric flavoenzymes that catalyze the transfer of electrons from NADPH to oxidized thioredoxin substrate. Bacterial thiredoxin reductases represent a promising target for development of new antibiotics. We crystallized recombinant thioroedoxin reductase TrxB from Streptomyces coelicolor using the hanging drop vapor diffusion method.
    Trvalý link: http://hdl.handle.net/11104/0201125