Počet záznamů: 1

Cysteine proteases from bloodfeeding arthropod ectoparasites

  1. 1.
    0365983 - BC-A 2012 RIV US eng J - Článek v odborném periodiku
    Sojka, Daniel - Francischetti, I.M.B. - Calvo, E. - Kotsyfakis, Michalis
    Cysteine proteases from bloodfeeding arthropod ectoparasites.
    Advances in Experimental Medicine and Biology. Roč. 712, - (2011), s. 177-191 ISSN 0065-2598
    Grant CEP: GA AV ČR IAA600960910; GA AV ČR IAA600960811; GA AV ČR KJB600960911; GA MŠk(CZ) LC06009
    Výzkumný záměr: CEZ:AV0Z60220518
    Klíčová slova: TICK HAEMAPHYSALIS-LONGICORNIS * PROLIXUS STAL HEMIPTERA * YELLOW-FEVER MOSQUITO * BLOOD-MEAL DIGESTION * L-LIKE ENZYME * BOOPHILUS-MICROPLUS * RHODNIUS-PROLIXUS * CATHEPSIN-B * ASPARAGINYL ENDOPEPTIDASES/LEGUMAINS * PROTEOLYTIC ACTIVATION
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 1.093, rok: 2011

    Cysteine proteases have been discovered in various bloodfeeding ectoparasites. Here, we assemble the available information about the function of these peptidases and reveal their role in hematophagy and parasite development. While most of the data shed light on key proteolytic events that play a role in arthropod physiology, we also report on the association of cysteine proteases with arthropod vectorial capacity. With emphasis on ticks, specifically Ixodes ricinus, we finally propose a model about the contribution of cysteine peptidases to blood digestion and how their concerted action with other tick midgut proteases leads to the absorbance of nutrients by the midgut epithelial cells.
    Trvalý link: http://hdl.handle.net/11104/0201100