Počet záznamů: 1

The efficient synthesis of 2-arylpyrimidine acyclic nucleoside phosphonates using Liebeskind-Srogl cross-coupling reaction

  1. 1.
    0363154 - UOCHB-X 2012 RIV GB eng J - Článek v odborném periodiku
    Břehová, Petra - Česnek, Michal - Dračínský, Martin - Holý, Antonín - Janeba, Zlatko
    The efficient synthesis of 2-arylpyrimidine acyclic nucleoside phosphonates using Liebeskind-Srogl cross-coupling reaction.
    Tetrahedron. Roč. 67, č. 38 (2011), s. 7379-7385 ISSN 0040-4020
    Grant CEP: GA MŠk 1M0508
    Výzkumný záměr: CEZ:AV0Z40550506
    Klíčová slova: Liebeskind-Srogl cross-coupling * acyclic nucleoside phosphonates * pyrimidines * arylboronic acids * microwave
    Kód oboru RIV: CC - Organická chemie
    Impakt faktor: 3.025, rok: 2011

    A series of novel acyclic nucleoside phosphonates with various aryls attached to the C-2 position of the pyrimidine moiety has been prepared using the Liebeskind-Srogl cross-coupling protocol. The reactions of highly functionalised 2-(methylsulfanyl)pyrimidines with various arylboronic acids were studied and optimised.
    Trvalý link: http://hdl.handle.net/11104/0199214