Počet záznamů: 1

Paramutation of tobacco transgenes by small RNA-mediated transcriptional gene silencing

  1. 1.
    0360303 - BFU-R 2012 RIV US eng J - Článek v odborném periodiku
    Crhák Khaitová, Lucie - Fojtová, M. - Křížová, Kateřina - Lunerová Bedřichová, Jana - Fulneček, Jaroslav - Depicker, A. - Kovařík, Aleš
    Paramutation of tobacco transgenes by small RNA-mediated transcriptional gene silencing.
    Epigenetics. Roč. 6, č. 5 (2011), s. 650-660 ISSN 1559-2294
    Grant CEP: GA ČR(CZ) GD204/09/H002; GA MŠk(CZ) LC06004
    Grant ostatní: GA ČR(CZ) GPP501/11/P667
    Výzkumný záměr: CEZ:AV0Z50040507; CEZ:AV0Z50040702
    Klíčová slova: transcriptional gene silencing * transgene epialleles * DNA methylation
    Kód oboru RIV: BO - Biofyzika
    Impakt faktor: 4.318, rok: 2011

    In this work we show that the sensitivity of transgene loci to inherited silencing (paramutation) induced in trans by small RNA molecules depends on the structure and epigenetic state of target. The complex inverted repeat loci with methylation in the coding region are generally more sensitive than single copy insertions.
    Trvalý link: http://hdl.handle.net/11104/0197884