Počet záznamů: 1

Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone

  1. 1.
    0360252 - UBO-W 2012 RIV GB eng J - Článek v odborném periodiku
    Wang, L. - Luzynski, K. - Pool, J. E. - Janoušek, V. - Dufková, Petra - Vyskočilová, Martina - Teeter, K. C. - Nachman, M. W. - Munclinger, P. - Macholán, Miloš - Piálek, Jaroslav - Tucker, P. K.
    Measures of linkage disequilibrium among neighbouring SNPs indicate asymmetries across the house mouse hybrid zone.
    Molecular Ecology. Roč. 20, č. 14 (2011), s. 2985-3000 ISSN 0962-1083
    Grant CEP: GA ČR GA206/08/0640
    Grant ostatní:NSF(US) DEB0746560
    Výzkumný záměr: CEZ:AV0Z60930519; CEZ:AV0Z50450515
    Klíčová slova: house mouse * hybrid zones * linkage disequilibrium * SNP markers
    Kód oboru RIV: EG - Zoologie
    Impakt faktor: 5.522, rok: 2011

    Theory predicts that naturally occurring hybrid zones between genetically distinct taxa can move over space and time as a result of selection and/or demographic processes. However, direct observations of hybrid zone movement are difficult to make unless the zone is moving rapidly. Here, evidence for movement in the house mouse Mus musculus domesticus x M. m. musculus hybrid zone is provided using measures of LD and haplotype structure among neighbouring SNP markers from across the genome. Local populations of mice across two transects in Germany and the Czech Republic were sampled, and a total of 1301 mice were genotyped at 1401 markers from the nuclear genome. Empirical measures of LD provide evidence for extinction and (re)colonization in single populations and, together with simulations, suggest hybrid zone movement because of either geography-dependent asymmetrical dispersal or selection favouring one subspecies over the other.
    Trvalý link: http://hdl.handle.net/11104/0197848