Počet záznamů: 1

NMR Structure and Action on Nicotinic Acetylcholine Receptors of Water-soluble Domain of Human LYNX1

  1. 1.
    0359731 - FGU-C 2012 RIV US eng J - Článek v odborném periodiku
    Lyukmanova, E. N. - Shenkarev, Z. O. - Shulepko, M. A. - Mineev, K. S. - D´Hoedt, D. - Kasheverov, I. E. - Filkin, S. Yu. - Krivolapova, A. P. - Janíčková, Helena - Doležal, Vladimír - Dolgikh, D. A. - Arseniev, A. S. - Bertrand, D. - Tsetlin, V.I. - Kirpichnikov, M. P.
    NMR Structure and Action on Nicotinic Acetylcholine Receptors of Water-soluble Domain of Human LYNX1.
    Journal of Biological Chemistry. Roč. 286, č. 12 (2011), s. 10618-10627 ISSN 0021-9258
    Grant CEP: GA ČR(CZ) GA305/09/0681
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: NMR structure * nicotinic acetylcholine receptor * water-soluble domain
    Kód oboru RIV: FH - Neurologie, neurochirurgie, neurovědy
    Impakt faktor: 4.773, rok: 2011

    NMR and functional analysis both demonstrate that ws-LYNX1 is an appropriate model to shed light on the mechanism of LYNX1 action. Computer modeling, based on ws-LYNX1 NMR structure and AChBP x-ray structure, revealed a possible mode of ws-LYNX1 binding
    Trvalý link: http://hdl.handle.net/11104/0197461