Počet záznamů: 1

Immunocytochemical demonstration of M1 muscarinic acetylcholine receptors at the presynaptic and postsynaptic membranes of rat diaphragm endplates

  1. 1.
    0359261 - FGU-C 2012 RIV CZ eng J - Článek v odborném periodiku
    Malomouzh, A. I. - Arkhipova, S. S. - Nikolsky, E. E. - Vyskočil, František
    Immunocytochemical demonstration of M1 muscarinic acetylcholine receptors at the presynaptic and postsynaptic membranes of rat diaphragm endplates.
    Physiological Research. Roč. 60, č. 1 (2011), s. 185-188 ISSN 0862-8408
    Grant CEP: GA AV ČR(CZ) IAA500110905; GA ČR GA202/09/0806
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: skeletal muscle * M1 muscarinic receptor
    Kód oboru RIV: ED - Fyziologie
    Impakt faktor: 1.555, rok: 2011

    M1-muscarinic acetylcholine (ACh) receptors (M1R) were directly demonstrated immunocytochemically in electronmicroscopic images of rat diaphragm neuromuscular junctions (NMJ). Specific electron-dense granules were located at presynaptic nerve ending membranes and in the sarcolemma in the depths of postsynaptic folds. This first visualization of M1R on both sides of the NMJ is in agreement with previous pharmacological data on the regulatory role of M1R in quantal and non-quantal ACh release
    Trvalý link: http://hdl.handle.net/11104/0197075