Počet záznamů: 1

Surface Plasmon Resonance Biosensor for Rapid Label-Free Detection of Microribonucleic Acid at Subfemtomole Level

  1. 1.
    0358219 - URE-Y 2011 RIV US eng J - Článek v odborném periodiku
    Šípová, Hana - Zhang, S.-Ch. - Dudley, A.M. - Galas, D. - Wang, K. - Homola, Jiří
    Surface Plasmon Resonance Biosensor for Rapid Label-Free Detection of Microribonucleic Acid at Subfemtomole Level.
    Analytical Chemistry. Roč. 82, č. 24 (2010), s. 10110-10115 ISSN 0003-2700
    Grant CEP: GA AV ČR KAN200670701
    Výzkumný záměr: CEZ:AV0Z20670512
    Klíčová slova: surface plasmon resonance * microRNA * cancer diagnostics * biosensor
    Kód oboru RIV: JB - Senzory, čidla, měření a regulace
    Impakt faktor: 5.874, rok: 2010

    MicroRNAs (miRNAs) present an important target for medical diagnostics of various serious diseases. We report a novel method for rapid and sensitive miRNA detection and quantization using high-performance portable surface plasmon resonance (SPR) sensor combined with a DNA*RNA antibody-based assay. The new approach allows detecting miRNA at levels down to high attomoles in less than 30 minutes. The methodology is found to yield results which agree well with established methods for miRNA detection.
    Trvalý link: http://hdl.handle.net/11104/0196316
    Název souboruStaženoVelikostKomentářVerzePřístup
    UFE 0358219.pdf91.7 MBJinávyžádat