Počet záznamů: 1

Structural Insights into the Function of P2X4: An ATP-Gated Cation Channel of Neuroendocrine Cells

  1. 1.
    0355649 - FGU-C 2011 RIV US eng J - Článek v odborném periodiku
    Stojilkovic, S. S. - Yan, Z. - Obšil, T. - Zemková, Hana
    Structural Insights into the Function of P2X4: An ATP-Gated Cation Channel of Neuroendocrine Cells.
    Cellular and Molecular Neurobiology. Roč. 30, č. 8 (2010), s. 1251-1258 ISSN 0272-4340
    Grant CEP: GA AV ČR(CZ) IAA500110910; GA AV ČR(CZ) IAA501110801
    Výzkumný záměr: CEZ:AV0Z50110509
    Klíčová slova: ATP-gated receptor channels * gating * ivermectin
    Kód oboru RIV: ED - Fyziologie
    Impakt faktor: 2.423, rok: 2010

    The P2X4 receptor is a member of a family of ATP-gated cation channels, which are composed of three subunits, each having two transmembrane domains linked by a large extracellular loop and intracellularly located N- and C-termini. Recent crystallization of zebrafish P2X4 not only provided the possibility for re-interpretation of data generated by site-directed mutagenesis but also to progress in further work on structural-functional characterization
    Trvalý link: http://hdl.handle.net/11104/0194368