Počet záznamů: 1
Knockdown of F1 epsilon subunit decreases mitochondrial content of ATP synthase and leads to accumulation of subunit c
- 1.0355560 - FGÚ 2011 RIV NL eng J - Článek v odborném periodiku
Havlíčková, Vendula - Kaplanová, Vilma - Nůsková, Hana - Drahota, Zdeněk - Houštěk, Josef
Knockdown of F1 epsilon subunit decreases mitochondrial content of ATP synthase and leads to accumulation of subunit c.
Biochimica Et Biophysica Acta-Bioenergetics. Roč. 1797, 6-7 (2010), s. 1124-1129. ISSN 0005-2728. E-ISSN 1879-2650.
[European Bioenergetics Conference /16./. Warsaw, 17.07.2010-22.07.2010]
Grant CEP: GA MŠMT(CZ) 1M0520; GA MZd(CZ) NS9759
Grant ostatní: Univerzita Karlova(CZ) 97807
Výzkumný záměr: CEZ:AV0Z50110509
Klíčová slova: ATP synthase * biogenesis * mitochondria
Kód oboru RIV: EB - Genetika a molekulární biologie
Impakt faktor: 5.132, rok: 2010
Silencing in HEK293 cell line by RNAi of ATP5E gene encoding the epsilon subunit resulted in inhibition of biogenesis of ATP synthase and accumulation of hydrophobic subunit c of the rotor structure of the enzyme. Results indicate a regulatory role of the smallest subunit of the catalytic F1 part of the enzyme in biosynthesis and assembly of mammalian ATP synthase complex
Trvalý link: http://hdl.handle.net/11104/0194304
Počet záznamů: 1