Počet záznamů: 1

Molecular mass spectrometry imaging in biomedical and life science research

  1. 1.
    0354266 - MBU-M 2011 RIV DE eng J - Článek v odborném periodiku
    Pól, Jaroslav - Strohalm, Martin - Havlíček, Vladimír - Volný, Michael
    Molecular mass spectrometry imaging in biomedical and life science research.
    Histochemistry and Cell Biology. Roč. 134, č. 5 (2010), s. 423-443 ISSN 0948-6143
    Grant CEP: GA MŠk LC545; GA ČR GPP206/10/P018
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: Mass spectrometry * Chemical imaging * Molecular imaging
    Kód oboru RIV: EE - Mikrobiologie, virologie
    Impakt faktor: 4.727, rok: 2010

    This review describes the current state of mass spectrometry imaging (MSI) in life sciences. A brief overview of mass spectrometry principles is presented followed by a thorough introduction to the MSI workflows, principles and areas of application. Three major desorptionionization techniques used in MSI, namely, secondary ion mass spectrometry (SIMS), matrix-assisted laser desorption ionization (MALDI), and desorption electrospray ionization (DESI) are described, and biomedical and life science imaging applications of each ionization technique are reviewed. A separate section is devoted to data handling and current challenges and future perspectives are briefly discussed at the end
    Trvalý link: http://hdl.handle.net/11104/0193307