Počet záznamů: 1

Dendritic cell-based vaccines for the therapy of experimental tumors

  1. 1.
    0352627 - UMG-J 2011 RIV GB eng J - Článek v odborném periodiku
    Piasecka, E.P. - Indrová, Marie
    Dendritic cell-based vaccines for the therapy of experimental tumors.
    Immunotherapy. Roč. 2, č. 2 (2010), s. 257-268 ISSN 1750-743X
    Grant CEP: GA AV ČR IAA500520807; GA ČR GA301/09/1024; GA MZd NS10660
    Grant ostatní:Polish Ministry of Science and Higher Education(PL) NN401235334
    Výzkumný záměr: CEZ:AV0Z50520514
    Klíčová slova: dendritic cells * preparation of vaccines * experimental tumors
    Kód oboru RIV: EB - Genetika a molekulární biologie
    Impakt faktor: 0.542, rok: 2010

    Dendritic cells (DCs ), potent antigen-presenting cells (APC) are able to link the innate and adaptive immune system. Many studies have been focused on different immunotherapeutic approaches to apply DCs as tools improving anticancer therapy. Although the benefit of DC-based vaccination during anticancer therapy have been reported, the general knowledge about the ultimate methods of DC-vaccine preparation still remains unsatisfied. Additionally, some remote effects of different forms of DC-vaccine application require broader elaboration using animal model studies. This review summarizes the effects of the application of antigen-stimulated and/or genetically modified DCs used as vaccines for the treatment of experimental tumors.
    Trvalý link: http://hdl.handle.net/11104/0192097