Počet záznamů: 1

Oxidative cleavage of 3beta-acetoxy-21-oxolup-18-en-28-oic acid by ruthenium tetroxide

  1. 1.
    0351597 - UOCHB-X 2011 RIV UZ eng J - Článek v odborném periodiku
    Kvasnica, Miroslav - Spáčilová, Pavla - Buděšínský, Miloš - Hajdúch, M. - Sarek, J.
    Oxidative cleavage of 3beta-acetoxy-21-oxolup-18-en-28-oic acid by ruthenium tetroxide.
    Chemistry of Natural Compounds. Roč. 46, č. 4 (2010), s. 545-548 ISSN 0009-3130
    Grant ostatní:GA ČR(CZ) GA305/09/1216
    Výzkumný záměr: CEZ:AV0Z40550506
    Klíčová slova: lupane triterpenoids * oxidation * ruthenium tetroxide * cleavage * decarboxylation
    Kód oboru RIV: CC - Organická chemie
    Impakt faktor: 0.693, rok: 2010

    3Acetoxy-21-oxolup-18-en-28-oic acid was used for oxidative cleavage by ruthenium tetroxide in a biphasic system. Tricyclic and tetracyclic acids and their derivatives were prepared. All prepared compounds were tested on cytotoxic activity against CEM tumor cell. Some of them showed activity in low micromolar concentrations.
    Trvalý link: http://hdl.handle.net/11104/0191314