Počet záznamů: 1
Measurement variation determines the gene network topology reconstructed from experimental data: a case study of the yeast cyclin network
- 1.0351526 - MBÚ 2011 RIV US eng J - Článek v odborném periodiku
To, C. Ch. - Vohradský, Jiří
Measurement variation determines the gene network topology reconstructed from experimental data: a case study of the yeast cyclin network.
FASEB Journal. Roč. 24, č. 9 (2010), s. 3468-3478. ISSN 0892-6638. E-ISSN 1530-6860
Grant CEP: GA ČR GA310/07/1009
Výzkumný záměr: CEZ:AV0Z50200510
Klíčová slova: numerical modeling * genetic programming * cell-cycle
Kód oboru RIV: EE - Mikrobiologie, virologie
Impakt faktor: 6.515, rok: 2010
Inference of the topology of gene regulatory networks from experimental data is one of the primary challenges of systems biology. In an example of a genetic network of cyclins in the yeast cell cycle, we analyzed static genome-wide location data together with microarray kinetic measurements using a recurrent neural network-based model of gene expression and a newly developed, unbiased algorithm based on evolutionary programming principles
Trvalý link: http://hdl.handle.net/11104/0191261
Počet záznamů: 1