Počet záznamů: 1

Do we need new antibiotics? The search for new targets and new compounds

  1. 1.
    0351521 - MBU-M 2011 RIV DE eng J - Článek v odborném periodiku
    Spížek, Jaroslav - Novotná, Jitka - Řezanka, Tomáš - Demain, L. A.
    Do we need new antibiotics? The search for new targets and new compounds.
    Journal of Industrial Microbiology & Biotechnology. Roč. 37, č. 12 (2010), s. 1241-1248 ISSN 1367-5435
    Výzkumný záměr: CEZ:AV0Z50200510
    Klíčová slova: Antibiotics * Infectious diseases * Antibiotic resistance
    Kód oboru RIV: EE - Mikrobiologie, virologie
    Impakt faktor: 2.416, rok: 2010

    Resistance to antibiotics and other antimicrobial compounds continues to increase. There are several possibilities for protection against pathogenic microorganisms, for instance, preparation of new vaccines against resistant bacterial strains, use of specific bacteriophages, and searching for new antibiotics. The antibiotic search includes: (1) looking for new antibiotics from nontraditional or less traditional sources, (2) sequencing microbial genomes with the aim of finding genes specifying biosynthesis of antibiotics, (3) analyzing DNA from the environment (metagenomics), (4) reexamining forgotten natural compounds and products of their transformations, and (5) investigating new antibiotic targets in pathogenic bacteria
    Trvalý link: http://hdl.handle.net/11104/0191257