Počet záznamů: 1

Comparative Ultrastructure of Langerhans-Like Cells in Spleens of Ray-Finned Fishes (Actinopterygii)

  1. 1.
    0350374 - BC-A 2011 RIV US eng J - Článek v odborném periodiku
    Lovy, J. - Wright, G. M. - Speare, D. J. - Tyml, Tomáš - Dyková, Iva
    Comparative Ultrastructure of Langerhans-Like Cells in Spleens of Ray-Finned Fishes (Actinopterygii).
    Journal of Morphology. Roč. 271, č. 10 (2010), s. 1229-1239 ISSN 0362-2525
    Grant CEP: GA MŠk LC522
    Výzkumný záměr: CEZ:AV0Z60220518
    Klíčová slova: fish * cyprinidae * halibut * dendritic cells * Langerhans cell * Birbeck granules * ultrastructure
    Kód oboru RIV: GJ - Choroby a škůdci zvířat, veterinární medicína
    Impakt faktor: 1.773, rok: 2010

    We studied the morphology and occurrence of splenic Langerhans-like (LL) cells in species representing 11 orders of ray-finned fishes, Actinopterygii. LL cells were frequent in spleen tissue of species among Cypriniformes, Esociformes, Salmoniformes, and Pleuronectiformes. These cells contained granules which resembled Birbeck granules known to occur in mammalian Langerhans cells. The ultrastructure of BL granules across the species is discussed. Additionally, multivesicular bodies were present within the cytoplasm and large aggregates of exosomes were observed closely associated with the plasma membrane suggesting their release from the cells. These structures are discussed in relation to mammalian dendritic cells. Macrophages found in some species contained lysosomes and residual bodies with structures resembling Birbeck granules. These granules and cells were clearly distinct from LL cells.
    Trvalý link: http://hdl.handle.net/11104/0190391