Počet záznamů: 1

Genomic characterization of severe acute respiratory syndrome-related coronavirus in European bats and classification of coronaviruses based on partial RNA-dependent RNA polymerase gene sequences

  1. 1.
    0349459 - UBO-W 2011 RIV US eng J - Článek v odborném periodiku
    Drexler, J. F. - Gloza-Rausch, F. - Glende, J. - Corman, V. M. - Muth, D. - Goettsche, M. - Seebens, A. - Niedrig, M. - Pfefferle, S. - Yordanov, S. - Zhelyazkov, L. - Hermanns, U. - Vallo, Peter - Lukashev, A. - Müller, M. A. - Deng, H. - Herrler, G. - Drosten, C.
    Genomic characterization of severe acute respiratory syndrome-related coronavirus in European bats and classification of coronaviruses based on partial RNA-dependent RNA polymerase gene sequences.
    Journal of Virology. Roč. 84, č. 21 (2010), s. 11336-11349 ISSN 0022-538X
    Výzkumný záměr: CEZ:AV0Z60930519
    Klíčová slova: cross-species transmission * SARS-like coronaviruses * reservoir hosts * horseshoe bats
    Kód oboru RIV: EE - Mikrobiologie, virologie
    Impakt faktor: 5.189, rok: 2010

    The paper evaluates coronaviruses (CoV) in rhinolophid and vespertilionid bat species common in Europe. Rhinolophids were shown to carry severe acute respiratory syndrome (SARS)-related CoV at high frequencies and concentrations, as well as two Alphacoronavirus clades Three other CoV clades present in Miniopterus bats in China were also present in European Miniopterus bats. An additional novel Alphacoronavirus clade was detected in Nyctalus leisleri. A CoV grouping criterion was developed by comparing amino acid identities across an 816-bp fragment of the RNA-dependent RNA polymerases of all accepted mammalian CoV species. Strict associations with host bat genera were confirmed for six independent CoV groups represented simultaneously in China and Europe. A SARS-related virus from a Bulgarian specimens of Rhinolophus blasii bat was fully sequenced. This study underlines the importance of assessments of the zoonotic potential of widely distributed bat-borne CoV.
    Trvalý link: http://hdl.handle.net/11104/0189694