Počet záznamů: 1

Cycloolefin-Copolymer/Polyethylene (COC/PE) Blend Assists with the Creation of New Articular Cartilage

  1. 1.
    0349339 - UFCH-W 2011 RIV DE eng J - Článek v odborném periodiku
    Petrtýl, M. - Bastl, Zdeněk - Kruliš, Zdeněk - Hulejová, H. - Polanská, M. - Lísal, J. - Danešová, J. - Černý, P.
    Cycloolefin-Copolymer/Polyethylene (COC/PE) Blend Assists with the Creation of New Articular Cartilage.
    Macromolecular Symposia. 294-I, - (2010), s. 120-132 ISSN 1022-1360
    Grant CEP: GA ČR GA106/06/0761
    Výzkumný záměr: CEZ:AV0Z40400503; CEZ:AV0Z40500505
    Klíčová slova: articular cartilage * biomaterials * cycloolefin-copolymer blend
    Kód oboru RIV: CF - Fyzikální chemie a teoretická chemie

    It is shown that the initial biomechanical stability of the applied COC/PE blend in the treated tissue locality, the initial integrity of biomaterials substituting the subchondral bone by polymer implant, the initial bearing capacity and the vertical position of these biomaterials have a mayor influence on the regeneration of new articular cartilage and subchondral bone. These aspects are essential for a prosperous treatment of osteochondral defects. Results reveal that the initial biomechanical stiffness of materials (substituting the subchondral bone) has a fundamental influence on both the quality and the quantity of new articular cartilage and subchondral bone. Research is also aimed at the application of suitable biologically tolerated polymer material, its surface modifications, verifications of the vertical position of implants in relation to the articular cartilage surface and ensuring the initial biomechanical stability of the polymer implant.
    Trvalý link: http://hdl.handle.net/11104/0189605